University College Cork
Ireland
History
Since 2019, The Network connects researchers and stakeholders to harness the potential of iPSCs in understanding mental disorders and discovering new drug treatments. It supports education, training, and dissemination, and advocates for minimal quality standards in iPSC research.
The establishment of our network resulted in several collaborative projects between our members and members of other ECNP networks. Bringing the iPSC technology to use in various aspects of neuroscience such as diagnosis, prediction, prevention, and neuropharmacology is of great importance in mental disorders.
Core members
Member name | Institution | City | Country |
|---|---|---|---|
Carine Ben Adiba | CHUV | Lausanne | Switzerland |
Oliver Brüstle | University of Bonn | Bonn | Germany |
Luigia Ginetta Collo | University of Brescia | Brescia | Italy |
Edna Grünblatt | University of Zürich | Zürich | Switzerland |
Adrian Harwood | Cardiff University | Cardiff | United Kingdom |
Rhiannon McNeil | University Hospital Würzburg | Würzburg | Germany |
Jeroen Pasterkamp | University Medical Center Utrecht | Utrecht | The Netherlands |
Marie-Claude Potier | ICM, Salpetrière | Paris | France |
János Réthelyi | Semmelweis University | Budapest | Hungary |
Tanja Sheldrick-Michel | University of Southern Denmark | Odense | Denmark |
Erik Smedler | University of Gothenburg | Goteborg | Sweden |
Anthony C. Vernon | King's College London | London | United Kingdom |
Shell members
| Member name | Institution | City | Country |
| Maija Castren | University of Helsinki | Helsinki | Finland |
| Anna Falk | Karolinska Institutet | Stockholm | Sweden |
| Silvana Galderisi | University of Campania “Luigi Vanvitelli” | Naples | Italy |
| Doris Gruber-Schoffnegger | Evotec SE | Hamburg | Germany |
| Tomas Kasparek | Masaryk University | Brno | Czech Republic |
| Armida Mucci | University of Campania “Luigi Vanvitelli” | Naples | Italy |
| Carlo Sala | CNR Neuroscience Institute | Milan | Italy |
| Deepak P. Srivastava | King's College London | London | United Kingdom |
Early Career Academy member
| Member name | Institution | City | Country |
| Amalie Couch | University of Oxford | Oxford | United Kingdom |
iPSC webinar series
The iPSC webinar series showcases the latest advances in iPSC-based neuropsychiatric research.
These online series, led by Early Career Scientists within the Network, aim to promote the sharing of knowledge and ideas across countries, advance the field of iPSC-based neuropsychiatry, and providing networking and training opportunities for participants.
Past webinars from the series are not available on-demand, but you can check upcoming webinars.
Publications
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2022Eichmüller & Knoblich
Human cerebral organoids — a new tool for clinical neurology research
Nature reviews neurology -
2022Eichmüller et al.
Amplification of human interneuron progenitors promotes brain tumors and neurological defects
Science -
2021Adhya et al.
Atypical neurogenesis in induced pluripotent stem cells from autistic individuals
Biological Psychiatry -
2023Polit et al.
Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders
Neuroscience Applied -
2024Kittel-Schneider et al.
Recent developments in human cell models in mental disorders
Neuroscience Applied -
2020McNeil et al.
Mental health dished up-the use of iPSC models in neuropsychiatric research
Journal of Neural Transmission -
2024Yde Ohki et al.
Correspondence to “Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca2+ entry and accelerated differentiation” by Hewitt et al.(PMID: 37402854)
Molecular Psychiatry -
2022Yde Ohki et al.
Promising Developments in the Use of Induced Pluripotent Stem Cells in Research of ADHD
New Discoveries in the Behavioral Neuroscience of Attention-Deficit Hyperactivity Disorder -
2024Couch et al.
Transcriptional and cellular response of hiPSC-derived microglia-neural progenitor co-cultures exposed to IL-6
Brain, Behavior, and Immunity -
2024Pavlinek et al.
Using Organoids to Model Sex Differences in the Human Brain
Biological Psychiatry Global Open Science -
2023Couch et al.
Acute IL-6 exposure triggers canonical IL6Ra signaling in hiPSC microglia, but not neural progenitor cells
Brain, Behavior, and Immunity -
2022Solomon et al.
Heterozygous expression of the Alzheimer's disease-protective PLCγ2 P522R variant enhances Aβ clearance while preserving synapses
Cellular and Molecular Life Sciences -
2020Warre-Cornish et al.
Interferon-γ signaling in human iPSC-derived neurons recapitulates neurodevelopmental disorder phenotypes
Science advances