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Pharmacogenomics and Transcriptomics Network

Aiming to accelerate precision medicine by focusing on the genetic and molecular factors that influence psychiatric treatment response. Its goals include identifying biosignatures for treatment (non-)response, enhancing clinical trial strategies, and facilitating knowledge transfer to improve patient outcomes. By fostering collaboration among Centres of Excellence and industry partners, the Network seeks to create a data biorepository, expand research, and enable the clinical integration of findings.

History

The Pharmacogenomics and Transcriptomics Network was formed under the ECNP initiative to address the need for collaborative research in pharmacogenomics and transcriptomics of neuropsychiatric disorders. Although genetic testing revolutionized psychiatric care after the Human Genome Project, the challenges in treatment response persisted. The ECNP-led initiative strives to unite centres of excellence across Europe to bridge these gaps, promoting a coordinated approach to research, education, and clinical practice, focusing on pharmacogenomics and transcriptomics. Building on the success of previous genetic studies, the Network aims to advance understanding of treatment response, foster interdisciplinary collaboration, and establish a clinical translation in precision medicine.

Bernhard Baune

University of Münster
Germany

Chair
Alessandra Minelli

University of Brescia
Italy

Co-chair
Core members
Member name Institution City Country

Bernhard Baune

University of Münster

Münster

Germany

Mara Dierssen

Centre for Genomic Regulation

Barcelona

Spain

Chiara Fabbri

King's College London

London

United Kingdom

Massimo Gennarelli

IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli

Brescia

Italy

Joost G.E. Janzing

Radboud University Nijmegen

Nijmegen

The Netherlands

Pietro Lio'

University of Cambridge

Cambridge

United Kingdom

Eduard Maron

University of Tartu

Tartu

Estonia

Divja Mehta

Queensland University of Technology

Brisbane

Australia

Alessandra Minelli

University of Brescia

Brescia

Italy

Claudia Pisanu

University of Cagliari

Cagliari

Italy

Marie-Claude Potier

Pitié-Salpêtrière Hospital

Paris

France

Filip Rybakowski

Poznan University of Medical Sciences

Poznan

Poland

Alessandro Serretti

University of Bologna

Bologna

Italy

Alessio Squassina

University of Cagliari

Cagliari

Italy

Roos van Westrhenen 

Erasmus MC

Rotterdam

The Netherlands
Shell members
Member name Institution City Country

Catherine Harmer

University of Oxford

Oxford

United Kingdom

Bjarke Ebert

Lundbeck A/S

Valby

Denmark

Oliver Howes

Imperial College London

London

United Kingdom
Early Career Academy member
Member name Institution City Country
Evelien Van Assche Universitätsklinikum Münster Münster Germany
Vincenzo Oliva Hospital Clinic- University of Barcelona- IDIBAPS- CIBERSAM Barcelona Spain

Publications