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Early Career Scientist (ECS) virtual seminar series
The iPSC Platform for Neuropsychiatry Network welcomes all interested researchers to our ECSs virtual seminar series. The virtual seminars will be hosted by one of the Network member institutions; they are free to attend and open to all ECSs (non-members are also welcome). Seminars will be presented by ECSs and will take a variety of forms, including research presentations, journal clubs and troubleshooting. We aim to promote the sharing of knowledge and ideas between ECSs in different countries in order to advance the field of iPSC-based neuropsychiatry, whilst additionally providing networking opportunities and training support. 

How to join
ECS who wish to join the next seminars can get in touch via e-mail with Rhiannon McNeill.

Future dates

  • 26 April 2023 at 16.00 CET (Central European Time)
    Programme is hosted by the group of Luigia Ginetta Collo.

  • 28 June 2023 at 16.00 CET (Central European Time)
    Programme is hosted by the group of Tanja Sheldrick-Michel.

Past dates

  • 8 March 2023 at 16.00 CET (Central European Time)
    Programme was hosted by the group of Jeroen Pasterkamp.
    Suzy Varderidou gave a presentation entitled: ‘Amyotrophic Lateral Sclerosis (ALS) propagation through Extracellular Vesicles and treatment strategies.‘

  • 22 February 2023 at 16.00 CET (Central European Time)
    Programme was hosted by the group of Edna Grünblatt.
    Two researchers, Cristine Marie Yde Ohki and Natalie Monet Walter, gave a presentation entitled: 'Investigating the cellular and molecular role of Wnt-pathway across neurodevelopmental processes in health and ADHD- possible modulation via methylphenidate or PUFAs'

  • 14 December 2022 at 16.00 CET (Central European Time)
    Programme hosted by the group of Armida Mucci
    ‘Innovative cellular models for schizophrenia: current findings and future approaches’

  • 26 October 2022 at 16.00 CEST (Central European Summer Time)
    Programme hosted by the Harwood Group had three talks:
    1) 'Effects of the dietary n-6 PUFAs on human neuronal function' by Karolina Dec, United Kingdom
    2) 'Investigating TSC function with an inducible Cas13' by Laura Kleckner, United Kingdom
    3) 'Kleefstra syndrome and miRNA regulation of NRSF/REST' by Jamie Wood, United Kingdom
  • 31 August 2022 at 16.00 CEST (Central European Summer Time)
    The seminar, hosted by Deepak Srivastav's group, had two talks:
    1) 'Analysing early neuronal differentiation in patient-derived induced pluripotent stem cells (iPSC) with NRXN1 mutations' by Lucia Dutan Polit, United Kingdom
    2) 'Translating genetic susceptibility to neurobiology of disease — understanding the role of psychosis risk candidate ZNF804A during synaptic development' by Laura Sichlinger, United Kingdom 
  • 1 June 2022
    The research group of Oliver Brüstle, Germany, gave two talks on the use of forward-programmed neurons to model candidate genes for neuropsychiatric diseases:
    1) Programmed neuronal subtypes for modeling neuropsychiatric disorders by Michael Peitz
    2) Generation of an isogenic human model of SYNGAP1 syndrome by Christina Au Yeung

Recommended publications

Editors  Year  Title  Link 
Alsaqati et al,
2022 NRSF/REST lies at the intersection between epigenetic regulation, miRNA-mediated gene control and neurodevelopmental pathways associated with Intellectual disability (ID) and Schizophrenia
Transl Psychiatry
Eichmüller et al.
2022 Amplification of human interneuron progenitors promotes brain tumors and neurological defects
Science 
Eichmüller & Knoblich
2022 Human cerebral organoids — a new tool for clinical neurology research
Nature reviews neurology
Ohki et al.
2022  Promising developments in use of induced pluripotent stem cells in research of ADHD Current Topics in Behavioral Neurosciences
Pavlinek et al,
2022 Interferon-γ exposure of human iPSC-derived neurons alters major histocompatibility complex I and synapsin protein expression
Front Psychiatry
Pearson et al.
2022 DNA Methylation Profiles of GAD1 in Human Cerebral Organoids of Autism Indicate Disrupted Epigenetic Regulation during Early Development
Int J Mol Sci
van Rhijn et al.
2022 Brunner syndrome associated MAOA mutations result in NMDAR hyperfunction and increased network activity in human dopaminergic neurons         
Neurobiology of Disease
Vuidel et al.
2022 High-content phenotyping of Parkinson's disease patient stem cell-derived midbrain dopaminergic neurons using machine learning classification
Stem cell Reports
Steg et al.
2021 Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons
Molecular Brain
Adhya et al.
2021 Atypical neurogenesis in induced pluripotent stem cells from autistic individuals
Biological Psychiatry
Couch et al.
2021 Maternal immune activation primes deficiencies in adult hippocampal neurogenesis Brain Behavior and Immunity
Adhya et al.
2021 Application of Airy beam light sheet microscopy to examine early neurodevelopmental structures in 3D hiPSC-derived human cortical spheroids
Molecular Autism  
Hathy et al.
2021 Generation of multiple iPSC clones from a male schizophrenia patient carrying de novo mutations in genes KHSRP, LRRC7, and KIR2DL1, and his parents
Stem Cell Research
Pavlinek et al.
2021 Interferon-gamma exposure of human iPSC-derived neurons alters major histocompatibility complex I and synapsinI protein expression
BioRxiv
Bhat et al.
2021 Attenuated transcriptional response to pro-inflammatory cytokines in schizophrenia hiPSC-derived neural progenitor cells
Brain Behavior and Immunity
Ilieva et al.
2021 Proteomic phenotype of cerebral organoids derived from autism spectrum disorder patients reveal disrupted energy metabolism, cellular components, and biological processes Molar Psychiatry
Collo et al.
2020 Negative symptoms of schizophrenia and dopaminergic transmission: translational models and perspectives opened by iPSC techniques
Frontiers in Neuroscience