ECNP icons scienific topics - ADHD


Droxidopa alters dopamine neuron and prefrontal cortex activity and improves attention-deficit/hyperactivity disorder-like behaviors in rats
lIke dela Peña, Guofang Shen, Wei-Xing Shia

Recommended by Damiana Leo, Belgium: `This article opens new possibilities to treat ADHD patients, the authors show that Droxidopa modulates hyperactivity in rats and exerts an excitatory effect on Prefrontal cortex neurons.’

In vivo imaging of dopamine D1 receptor and activated microglia in attention-deficit/hyperactivity disorder: a positron emission tomography study
Masamichi Yokokura et al

Recommended by Damiana Leo, Belgium: `PET analyses of 24 ADHD patients show that microglial activation and the D1R reduction as well as their aberrant interactions underpin the neurophysiological mechanism of ADHD.’

Cocaine-induced locomotor stimulation involves autophagic degradation of the dopamine transporter
Maged M Harraz et al

Recommended by Damiana Leo, Belgium: ´The paper shows that subnanomolar concentrations of cocaine elicit neural autophagy in vitro and in vivo.’