During the year, the Bipolar Disorders (BD) Network organises meetings for its members (also at the annual ECNP Congress).

Research projects

  • REALMENT (Using real-world big data from eHealth, biobanks and national registries, integrated with clinical trial data to improve outcome of severe mental disorders)

  • ENBREC (European Network of Bipolar Research Expert Centres)
    (FP7 HEALTH-2007-3.4-1, Disease networks of centres of reference, project number 223102; 2009-2011)

  • R-LiNK project (Optimizing response to lithium treatment through personalized evaluation of individuals with bipolar I disorder)
    (European Union’s Horizon 2020 Research and Innovation programme Under Grant Agreement no. 754907)

  • ENIGMA project

    (European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 602450)

  • CoMorMent (Predicting comorbid cardiovascular disease in individuals with mental disorder by decoding disease mechanisms)
    (European Union’s Horizon 2020 Research and Innovation programme Under Grant Agreement no. 847776)

Prevention of Severe Mental Disorders (PSMD) cluster
The Prevention of Mental Disorders and Mental Health Promotion PMD-MHP and the Bipolar Disorders Networks created the Prevention of Severe Mental Disorders (PSMD) cluster recognised by the project EBRA (European Brain Research Agenda)

Recommended publications

Journal and link to the article
Kessing et al.
2021 DSM-5 and ICD-11 criteria for bipolar disorder: Implications for the prevalence of bipolar disorder and validity of the diagnosis — A narrative review from the ECNP bipolar disorders network
European Neuropsychopharmacology
Manchia M et al.
2020  Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action
European Neuropsychopharmacology
Ching CRK, et al.
2020 What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group
Human Brain Mapping
Nunes A, et al.
2020  Using structural MRI to identify bipolar disorders — 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group
Molecular Psychiatry
Favre et al.
2019 Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega-and meta-analyses across 3033 individuals
Kaufmann et al.
2019 Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nature Neuroscience
Scott et al.
2019 Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative  International Journal of Bipolar Disorders
de Zwarte et al.
2019 The association between familial risk and brain abnormalities is disease specific: An ENIGMA -relatives study of schizophrenia and bipolar disorder
Biological Psychiatry
Cross-Disorder Group of the Psychiatric Genomics Consortium
2019 Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
Faurholt-Jepsen et al. 2019 Reporting guidelines on remotely collected electronic mood data in mood disorder (eMOOD) —recommendations. Translational Psychiatry
Stahl et al. 2019
Genome-wide association study identifies 30 loci associated with bipolar disorder.  Nature Genetics
Nunes et al. 2018
Using structural MRI to identify bipolar
disorders - 13 site machine learning study in 3020 individuals
from the ENIGMA Bipolar Disorders Working Group.
Molecular Psychiatry
Hibar et al. 2018
Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group. Molecular Psychiatry
Bauer et al.  2018
Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives.  Lancet Psychiatry
The Brainstorm Consortium et al.  2018
Analysis of shared heritability in common disorders of the brain.  Science
Bipolar Disorder and
Schizophrenia Working Group of the Psychiatric Genomics Consortium
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes. Cell
International Consortium on Lithium Genetics (ConLi+Gen) et al. 2018
Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study. JAMA Psychiatry
Bauer et al. 2017 Solar insolation in springtime influences age of onset of bipolar I disorder. Acta Psychiatrica Scandinavica
Witt et al. 2017
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.  Translational Psychiatry
Aas et al. 2016
The role of childhood trauma in bipolar disorders  International Journal of Bipolar Disorders 
Lagerberg et al.  2016
Cannabis use disorder is associated with greater illness severity in tobacco smoking patients with bipolar disorder.  Journal of Affective Disorders 
Bonnin et al. 2016
Functional remediation in bipolar disorder: 1-year follow-up of neurocognitive and functional outcome. British Journal of Psychiatry
Hibar et al.  2016
Subcortical volumetric abnormalities in bipolar disorder.  Molecular Psychiatry 
Vallarino et al. 2015
An evidence map of psychosocial interventions for the earliest stages of bipolar disorder  Lancet Psychiatry
Fountoulakis et al.  2015
Report of the WPA section of pharmacopsychiatry on the relationship of antiepileptic drugs with suicidality in epilepsy. International Journal of Psychiatry in Clinical Practice
Bauer et al. 2015
Influence of birth cohort on age of onset cluster analysis in bipolar I disorder. European Psychiatry
Arrasate et al. 2014
Affective dimensions as a diagnostic tool for bipolar disorder in first psychotic episodes European Psychiatry
Aas et al. 2014 Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders. Psychological Medicine
Bauer et al. 2014
Relationship between sunlight and the age of onset of bipolar disorder: an international multisite study  Journal of Affective Disorders 
Etain et al. 2013
Childhood trauma is associated with severe clinical characteristics of bipolar disorders.  The Journal of Clinical Psychiatry
Torrent et al. 2013
Long-term outcome of cognitive impairment in bipolar disorder. The Journal of Clinical Psychiatry 
Torrent et al.   2013
Efficacy of functional remediation in bipolar disorder: a multicenter randomized controlled study.  American Journal of Psychiatry
Barbato et al. 2013
Validation of the Italian version of the Functioning Assessment Short Test (FAST) for bipolar disorder.  Epidemiology and Psychiatric Sciences
Bourne et al.  2013
Neuropsychological testing of cognitive impairment in euthymic bipolar disorder: an individual patient data meta-analysis.  Acta Psychiatrica Scandinavica
Henry et al.  2013
European Network of Bipolar Research Expert Centre (ENBREC): a network to foster research and promote innovative care.  International Journal of Bipolar Disorders 
Etain et al. 2012 Clinical expression of bipolar disorder type I as a function of age and polarity at onset: convergent findings in samples from France and the United States. The Journal of Clinical Psychiatry
González-Pinto et al.  2012
Anxiety as a marker of severity in acute mania. Acta Psychiatrica Scandinavica 
Bauer et al.  2012
Impact of sunlight on the age of onset of bipolar disorder Bipolar disorder

Educational activities

  • 23 February 2021: Workshop on 'Ethics of Precision and Preventive Psychiatry' — 2 hours online event organised by PSMD Cluster of EBRA

Targeted Network Meetings