During the year, the Anxiety Disorders Network organises meetings for its members (also at the annual ECNP Congress)

'Lay expert panel for research' in anxiety disorders
In February 2013, the Networks initiative approved the ADRN proposal to convene a group of representatives from patient-led organisations focused on anxiety disorders, as a “lay expert panel” to inform subsequent proposals for research funding. The Network intended this panel to guide the development of future research proposals and to facilitate dissemination of research findings to as wide an audience as possible. The aim was to discuss currently met and unmet needs in the management of anxiety disorders, addressing public health aspects, as well as the management of affected individuals in primary, secondary and tertiary health services.

POLT-Q questionnaire for onset of illness and treatment latency
In February 2012, the ECNP Networks initiative approved funding for a collaborative project for the development of a questionnaire relating to the duration of illness and latency of treatment, led by the Milan centre (Altamura, dell’Osso), with advice from researchers in Santander and Southampton. Dr. Carlotta Palazzo described the development of the ‘psychopathological onset and latency to treatment questionnaire” (POLT-Q) at the ADRN meeting in October 2012. At that time, over 250 patients, with a range of psychiatric diagnoses, had contributed to this project. The questionnaire had been translated into an English language version, and its item content and feasibility were being examined within the mood disorders service in Southampton. Further development of the POLT-Q includes its translation into other languages. An examination of the medical notes of a sub-sample of participants will be undertaken to examine how responses on the POLT-Q compare to information previously collected within medical notes.


Research projects
EUSARNAD programme (Joint European and South African Research Network in Anxiety Disorders) funded by the European Commission, through the Marie Curie Actions (People) International Research Staff Exchange Scheme (PIRSES-GA-2010-269213) between October 2011 and September 2015. EUSARNAD built on the ADRN strengths and extended these by establishing firmer research collaboration with the University of Cape Town in South Africa. The research exchange shared knowledge and expertise among participating centres, in order to ensure a comprehensive translational research approach in anxiety disorders, relevant to the needs of developed and developing societies. This scheme: 1) allowed South African researchers to gain detailed first-hand experience of certain research methodologies in European centres; 2) helped European investigators to deepen understanding of the origin of anxiety disorders and problems in their management within an emerging country; and 3) thereby enhanced the relevance of translational research activity jointly conducted within Europe and South Africa to other developed and developing societies. Overall, 27 researchers took a secondment opportunity that initiated multidisciplinary and innovative collaborations with different research teams. If you would like to discover about some of the recent publications, click here.
You can find more info about the research on the EUSARNAD Colloquium report.

Recommended publications

Journal and link to the article
Liaugaudaite et al.
2020 Neurocognitive markers of suicidal ideation in patients with anxiety and mood disorders
International Journal of Psychiatry in Clinical Practice
Schiele et al.
2020  A neurobiological framework of separation anxiety and related phenotypes   European Neuropsychopharmacology
Vinkers et al
2020 Stress resilience during the coronavirus pandemic
European Neuropsychopharmacology
Liaugaudaite et al.
2020 Neurocognitive markers of suicidal ideation in patients with anxiety and mood disorder
International Journal of Psychiatry in Clinical Practice
Schiele et al.
Hypermethylation of the serotonin transporter gene promoter in panic disorder–Epigenetic imprint of comorbid depression?  European Neuropsychopharmacology
Uhlmann et al. 2019 Grey matter structural differences in alcohol-dependent individuals with and without comorbid depression/anxiety-an MRI study.  European Archives of Psychiatry and Clinical Neuroscience
Aghajani et al.
Interactions Between Oxytocin Receptor Gene Methylation and Callous-Unemotional Traits Impact Socioaffective Brain Systems in Conduct-Disordered Offenders
Biol Psychiatry Cogn Neurosci Neuroimaging
Matthies et al. 2018
Please don't leave me – separation anxiety in borderline personality disorder. Current Psychiatry Reports
Schiele et al.  2018 Oxytocin receptor gene variation, behavioural inhibition, and adult separation anxiety: Role in complicated grief. The World Journal of Biological Psychiatry
Ströhle et al. 2018 The Diagnosis and Treatment of Anxiety Disorders. Deutsches Ärzteblatt International
Schiele et al. 2018
Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders. Genes, Brain and Behavior 
Davies et al.
2017 Management of panic disorder in primary care   Prescriber
Bandelow et al. 2017 Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition.  The World Journal of Biological Psychiatry
Howells et al.  2017 Current and potential pharmacological and psychosocial interventions for anxiety symptoms and disorders in patients with schizophrenia: structured review.  Human Psychopharmacology
Bandelow et al. 2016
Biological markers for anxiety disorders, OCD and PTSD - a consensus statement. Part I: Neuroimaging and genetics. The World Journal of Biological Psychiatry
Sinclair et al. 2016
Attentional biases in patients with alcohol dependence: influence of coexisting psychopathology. Human Psychopharmacology
Breen et al. 2016
Systematic review of blood transcriptome profiling in neuropsychiatric disorders: guidelines for biomarker discovery. Human Psychopharmacology
Benson-Martin et al. 2016
Genetic mechanisms of electroconvulsive therapy response in depression. Human Psychopharmacology 
Breen et al.  2016
Candidate gene networks and blood biomarkers of methamphetamine-associated psychosis: an integrative RNA-sequencing report.  Translational Psychiatry
Howells et al. 2015
Can cognitive behaviour therapy beneficially influence arousal mechanisms in psychosis? Human Psychopharmacology
Geiger et al. 2014
Arousal and the attentional network in panic disorder  Human Psychopharmacology 
Cuzen et al. 2014 Unconscious habit systems in compulsive and impulsive disorders  Behavioral and Brain Sciences
Palazzo et al.  2014 Health literacy and the pharmacological treatment of anxiety disorders: a systematic review Human Psychopharmacology
Crawford et al.

Haplotype-based study of the association of alcohol and acetaldehyde-metabolising genes with alcohol dependence (with or without comorbid anxiety symptoms) in a Cape Mixed Ancestry population Metabolic Brain Disease
Pannekoek et al. 2014 Diagnosis and classification of hypochondriasis In: Starcevic et al., Hypochondriasis and health anxiety: A guide for clinicians.
Cuzen et al. 2013 Comorbidity of obsessive-compulsive disorder and substance use disorder: a new heuristic  Human Psychopharmacology  
Baldwin et al.
2013 EUSARNAD: the story so far African Journal of Psychiatry  
Pasche et al.  2013
"Craving": Exploring the components of the Desires for Alcohol Questionnaire (DAQ) and the relation to the severity of alcohol problems  Journal of Studies on Alcohol and Drugs  
Ainsworth et al. 2013 Attention control in mood and anxiety disorders: evidence from the anti-saccade task Human Psychopharmacology
Pannekoek et al. 2013
Advances in neuroimaging of panic disorders  Human Psychopharmacology
Fouche et al.  2013 Recent advances in the brain imaging of social anxiety disorder Human Psychopharmacology  
Van der Werff et al.  2013
Neuroimaging of resilience to stress: current state of affairs   Human Psychopharmacology  
Baldwin et al. 2013
Developing a European research network to address unmet needs in anxiety disorders Neuroscience and Biobehavioral Reviews
Dell'Osso et al.
Can long-term outcomes be improved by shortening the duration of untreated illness in psychiatric disorders: a conceptual framework Psychopathology
Ayling et al.  2012 Diffusion tensor imaging in anxiety disorders
Current Psychiatry Reports 
Pasche et al.  2012 Substance misuse trends in South Africa
Human Psychopharmacology  
Baldwin et al. 2012
A joint European and South African research network in anxiety disorders   Human Psychopharmacology  
Baldwin et al.  2010
Manifesto for a European anxiety disorders research network
European Neuropsychopharmacology  

Targeted Network Meetings

  • 'Adult separation anxiety disorder: boundaries, causes and potential treatment' (22 October 2014, after the 27th ECNP Congress in Berlin, Germany).
  • 'Anxiety disorders across the life spa'(10 October 2018, after the 31st ECNP Congress in Barcelona, Spain).