ADHD

 

Droxidopa alters dopamine neuron and prefrontal cortex activity and improves attention-deficit/hyperactivity disorder-like behaviors in rats
lIke dela Peña, Guofang Shen, Wei-Xing Shia

Recommended by Damiana Leo, Belgium: `This article opens new possibilities to treat ADHD patients, the authors show that Droxidopa modulates hyperactivity in rats and exerts an excitatory effect on Prefrontal cortex neurons.’

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In vivo imaging of dopamine D1 receptor and activated microglia in attention-deficit/hyperactivity disorder: a positron emission tomography study
Masamichi Yokokura et al

Recommended by Damiana Leo, Belgium: `PET analyses of 24 ADHD patients show that microglial activation and the D1R reduction as well as their aberrant interactions underpin the neurophysiological mechanism of ADHD.’

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Cocaine-induced locomotor stimulation involves autophagic degradation of the dopamine transporter
Maged M Harraz et al

Recommended by Damiana Leo, Belgium: ´The paper shows that subnanomolar concentrations of cocaine elicit neural autophagy in vitro and in vivo.’